The next SUP meeting will take place in Uppsala on the 10th of October, 2024.
The meeting will be held at Pharmetheus' new office, conveniently located just a 5-minute walk from the train station: Dragarbrunnsgatan 77, 5th floor, 753 19 Uppsala
The SUP Fall meeting is fully booked but please send an email to events@pharmetheus.com if you wish to be on the waiting list.
The theme for the fall meeting will be:
Semi-mechanistic models developed based on PK and/or PD data
A semi-mechanistic model in the pharmacometric domain typically borrows structure from the system it describes to such an extent that, at least some, parameters can be given physiological/pharmacological meaning. The model parameters are typically determined from the experimental data even if priors, either weak or strong, can be used for some of the parameters. Familiar examples are the Friberg model for myelosuppression and the target-mediated drug disposition models.”
Agenda - this might be updated with additional speakers
Evaluation of antibiotic effects using time-lapse microscopy Eva Wehrhahn, Uppsala University
Knowledge-driven drug development: from microphysiological systems to humans using scalable digital twins Oscar Silfvergren, Linköping University
Data-Driven Prediction of Postprandial Metabolic Response Using Dynamic Mode Decomposition Viktor Skantze, Chalmers
Mechanistic modeling of blood brain barrier breakdown and drug repair Daniel Röshammar, InSilicoTrials
Pharmacometrics for Combination Therapy in Oncology Marcus Baaz, Chalmers
Modeling direct and indirect drug effects on fasting plasma glucose, fasting serum insulin, and HbA1c interplay in subjects with type 2 diabetes mellitus Martin Bergstrand, Pharmetheus